What is the PULS Cardiac TestTM?

PULS (Protein Unstable Lesion Signature) is a simple blood test that measures the most clinically significant protein biomarkers that are present in the blood of individuals with active lesion formation and progression that is in danger of rupture leading to heart attack. Unstable Cardiac Lesion rupture is responsible for 75% of all heart attacks.

What are Unstable Cardiac Lesions and how do they cause most Heart Attacks?

The latest research shows that 75% of all Heart Attacks occur when an “unstable lesion” forms in the wall of the artery and eventually ruptures. A cardiac lesion begins to form from oxidized or damaged lipids that cause arterial injury. Just like with any other injury, the body responds to the arterial injury by sending white blood cells and stimulating the proliferation of smooth muscle cells in order to repair itself. However, instead of healing the injury, the white blood cells transform into lipid-laden foam cells that further perpetuate the damaged area. Over time, this ongoing process of continuous arterial injury and repair causes the damaged lipid core of the lesion to become unstable and prone to rupture – often with no warning signs or symptoms. When the lesion ruptures, it prompts a blood clot, which restricts blood flow and causes an immediate Heart Attack.

Why test for Unstable Cardiac Lesions?

Early detection of unstable cardiac lesions and likelihood of rupture allows for critical intervention and prevention strategies.
Current diagnostic and clinical CHD tools that rely on established clinical factors often do not identify, or often underestimate, patients who are in danger of having a Heart Attack. In fact, over 50% of individuals presenting with a severe cardiac event have at most one clinical factor or normal cholesterol levels.
Since most Heart Attacks occur with no previous signs or symptoms, there is a great need to identify a high population of individuals who may have Heart Disease, but may not have any signs or symptoms, before they experience a cardiac event.

Why should I consider getting my PULS Cardiac Test?

Unlike traditional tests for Heart Disease, the PULS Test can:
  • Detect the early stages disease
  • Diagnose the disease stage and progression of unstable cardiac lesion formation
  • Predict how likely the disease will cause an unstable cardiac lesion rupture or Heart Attack

Because, 80% of Heart Disease is preventable/reversible with early-detection and lifestyle modifications, you and your physician can work together on an appropriate prevention plan according to the latest clinical guidelines.

Is the PULS Test right for you?

The PULS Test is for patients 40 years or older who have had no previous history of a Heart Attack (myocardial infarction). Your healthcare provider will be able to determine if the PULS Cardiac Test is right for you.

Is there a Heart Disease test for patients under 40?

AHA Guidelines recommend getting a baseline CHD assessment in individuals starting at age 20. Basic and Expanded Lipid Profiles are baseline assessments available for patients under 40 years old. Contact Client Services at (866) 299-8998 for more information.

How can I get a PULS Cardiac Test?

The PULS Test must be ordered by a healthcare provider. Contact our Client Services team at (866) 299-8998 to request information to take to your physician, or to have one of our sales representatives contact your doctor directly on your behalf.

My physician isn’t familiar with this test, how can I help?

Contact our Client Services team at (866) 299-8998 and we would be happy to provide you or your physician with information about PULS. You may choose to present your doctor with additional information we send to you, or one of our sales representatives can contact your doctor’s office to tell them about this important advancement in the detection of coronary heart disease.

How is the PULS Cardiac Test performed?

The test itself is performed on a simple blood sample. Blood draws for the PULS Cardiac test are provided in a variety of convenient ways, based on your location. Contact Client Services at (866) 299-8998 for more information on how you can get your blood drawn for the PULS Test.

What is included in the PULS Test Results?

Your PULS test results will include:
  • Your personalized 5-Year Cardiac Profile with individual measurements for each of the proteins that contribute to your cumulative 5-year unstable cardiac lesion diagnosis and the likelihood of rupture (Heart Attack).
  • Your “Heart Age” which shows your Cardiac Score relative to your Age and Gender group.
  • Recommended lifestyle modifications that may help maintain or reduce your chances of a Heart Attack.
PULS Test results will allow your physician to then determine the most appropriate course of action based on current clinical guidelines.

My cholesterol is normal. Why would I need the PULS Test?

Cholesterol testing alone doesn’t provide a complete picture of cardiac health. In fact, 50% of Heart Attack victims have normal cholesterol or at most one clinical factor. As such, the role of dietary cholesterol in relation to CHD has been called into question in recent years as the US dietary guidelines are reevaluated.
The PULS Test goes beyond traditional testing to identify patients who may be unaware of their chances for the leading cause of Heart Attack (75%), and for whom early intervention can help.

Will my insurance pay for the PULS Test?

The PULS Cardiac Test is currently reimbursed by most insurance providers, including Medicare. Please check with your health care provider or insurance carrier to understand the coverage provided for the PULS Cardiac Test based on your insurance plan.